Endocrine Abstracts

Background: Kidney stones have been linked to chronic kidney disease and a higher probability of adverse cardiovascular events. Precise mechanisms that lead to these complications have not yet been elucidated. Most cases of kidney stones are idiopathic, related to metabolic disturbances like hypercalciuria, which often have a genetic background. There have been few reports of kidney stones associated with primary hyperaldosteronism (HA); however, the prevalence of HA in patien...

Objective: Trabecular bone score (TBS) is associated with an increased risk of prevalent and incident fractures. It has a role of fracture assessment in secondary osteoporosis related to diabetes, acromegaly and hyperparathyroidism and in glucocorticoid-induced osteoporosis. However, it is understudied as a marker of bone health in heart transplanted patients. The aim of our pilot study was to evaluate the effects of zoledronic acid (ZA) on bone health including TBS in this po...

Serum urate level has recently been associated with increased bone mineral density (BMD). Teriparatide, an osteoanabolic medication for osteoporosis, is associated with increased incidence of hyperuricemia. Hence, we hypothesized that changes in serum urate are associated with changes in BMD and procollagen type 1 N-terminal propeptide (P1NP) during treatment with teriparatide.We collected data from 151 women (mean age 72 years, mean BMI 26.6 kg/m2<...